ALDH2 Antikörper (AA 317-517)

Produktnummer ABIN1846467

Produktdetails anti-ALDH2 Antikörper

Target: ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))

Bindungsspezifität: AA 317-517

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ALDH2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (fixed cells) (IF/ICC)

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human ALDH2 (AA: 317-517) expressed in E. coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Details zu ALDH2

Target: ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))

Andere Bezeichnung: ALDH2 (ALDH2 Produkte)

Synonyme: aldh2 antikoerper, aldh2a antikoerper, zgc:63786 antikoerper, MGC80785 antikoerper, aldh-e2 antikoerper, aldhi antikoerper, aldm antikoerper, rf2b antikoerper, ALDH-E2 antikoerper, ALDHI antikoerper, ALDM antikoerper, Ahd-5 antikoerper, Ahd5 antikoerper, aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 1 antikoerper, aldehyde dehydrogenase 2 family (mitochondrial) L homeolog antikoerper, aldehyde dehydrogenase 2 family (mitochondrial) antikoerper, aldehyde dehydrogenase 2 antikoerper, aldehyde dehydrogenase antikoerper, aldehyde dehydrogenase (NAD(+)) antikoerper, hypothetical protein antikoerper, aldehyde dehydrogenase 2, mitochondrial antikoerper, aldh2.1 antikoerper, aldh2.L antikoerper, aldh2 antikoerper, ALDH2 antikoerper, RHA1_RS43090 antikoerper, aldH2 antikoerper, OE_RS03015 antikoerper, Aldh2 antikoerper

Hintergrund: This protein belongs to the aldehyde dehydrogenase family of proteins.Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism.Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations.Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme.A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme.The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer.This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix.Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molekulargewicht: 56.3 kDa

Gen-ID: 217