IFT74 Antikörper (C-Term)
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- Target Alle IFT74 Antikörper anzeigen
- IFT74 (Intraflagellar Transport Protein 74 Homolog (IFT74))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Ziege
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Klonalität
- Polyklonal
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Konjugat
- Dieser IFT74 Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB)
- Verwendungszweck
- CMG1 / CCDC2 / IFT74
- Sequenz
- KTIVDALHST SGN
- Kreuzreaktivität
- Human, Ratte
- Aufreinigung
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- Güteklasse
- Verified
- Immunogen
- Peptide with sequence C-KTIVDALHSTSGN, from the C Terminus of the protein sequence according to NP_001092692.1, NP_001092693.1, NP_079379.2, AAK77221.1.
- Isotyp
- IgG
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- Applikationshinweise
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Western Blot: Approx 70 kDa band observed in lysates of cell line HEK293 (calculated MW of 69.2 kDa according to AAK77221.1). The observed molecular weight corresponds to earlier findings in literature (Momeni et al, BMC Neurol. 2006 Dec 13,6:44., PMID: 17
Peptide ELISA: antibody detection limit dilution 1:32000.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Buffer
- Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Minimize freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
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Disruption of intraflagellar protein transport in photoreceptor cilia causes Leber congenital amaurosis in humans and mice." in: The Journal of clinical investigation, Vol. 121, Issue 6, pp. 2169-80, (2011) (PubMed).
: "Analysis of IFT74 as a candidate gene for chromosome 9p-linked ALS-FTD. ..." in: BMC neurology, Vol. 6, pp. 44, (2007) (PubMed).
: "
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Disruption of intraflagellar protein transport in photoreceptor cilia causes Leber congenital amaurosis in humans and mice." in: The Journal of clinical investigation, Vol. 121, Issue 6, pp. 2169-80, (2011) (PubMed).
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- Target
- IFT74 (Intraflagellar Transport Protein 74 Homolog (IFT74))
- Andere Bezeichnung
- IFT74 (IFT74 Produkte)
- Hintergrund
- IFT74, CCDC2, CMG-1, FLJ22621, MGC111562, intraflagellar transport 74 homolog (Chlamydomonas), capillary morphogenesis protein 1, coiled-coil domain containing 2, CMG1
- Gen-ID
- 80173, 313365
- NCBI Accession
- NP_001092692, NP_001092693, NP_079379
- Pathways
- Hedgehog Signalweg, Chromatin Binding
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