LRP5 Antikörper (Internal Region)

Produktnummer ABIN185410

Produktdetails anti-LRP5 Antikörper

Target: LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser LRP5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Verwendungszweck: LRP5

Sequenz: ERVEKTTGDK RT

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Güteklasse: Verified

Immunogen: Peptide with sequence C-ERVEKTTGDKRT, from the internal region of the protein sequence according to NP_002326.2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry: In paraffin embedded Human Liver shows weak cytoplasm staining in some hepatocytes. Recommended concentration: 2-4 μg/mL.

Western Blot: Approx 180 kDa band observed in lysates of cell line HepG2 (calculated MW of 179 kDa according to NP_002326.2). Recommended concentration: 1-3 μg/mL. Primary incubation was 1 hour. Preliminary testing was unsuccessful on Mouse Liver for this p

Peptide ELISA: antibody detection limit dilution 1:16000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Referenzen für anti-LRP5 Antikörper (ABIN185410)

Dong, Li, Li, Ren, Fan, Weng: "MicroRNA-23a-3p inhibitor decreases osteonecrosis incidence in a rat model." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 9331-9336, (2018) (PubMed).

Details zu LRP5

Target: LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))

Andere Bezeichnung: LRP5 (LRP5 Produkte)

Hintergrund: LRP5, low density lipoprotein receptor-related protein 5, HGNC:6697, BMND1, HBM, LR3, LRP7, OPPG, OPS, VBCH2, low density lipoprotein receptor-related protein 7, osteoporosis pseudoglioma syndrome, EVR1, EVR4, OPTA1, exudative vitreoretinopathy 1,

Gen-ID: 4041

NCBI Accession: NP_002326

Pathways: WNT Signalweg, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation