ACSL1 Antikörper (C-Term)

Produktnummer ABIN1881044

Produktdetails anti-ACSL1 Antikörper

Target: ACSL1 (Acsl1) (Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1))

Bindungsspezifität: AA 505-533, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACSL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ACSL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 505-533 amino acids from the C-terminal region of human ACSL1.

Klon: RB42775

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-ACSL1 Antikörper (ABIN1881044)

Phillips, Goumidi, Bertrais, Field, Cupples, Ordovas, Defoort, Lovegrove, Drevon, Gibney, Blaak, Kiec-Wilk, Karlstrom, Lopez-Miranda, McManus, Hercberg, Lairon, Planells, Roche: "Gene-nutrient interactions with dietary fat modulate the association between genetic variation of the ACSL1 gene and metabolic syndrome." in: Journal of lipid research, Vol. 51, Issue 7, pp. 1793-800, (2010) (PubMed).

Lu, Dollé, Imholz, van t Slot, Verschuren, Wijmenga, Feskens, Boer: "Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations." in: Journal of lipid research, Vol. 49, Issue 12, pp. 2582-9, (2008) (PubMed).

Mashek, Bornfeldt, Coleman, Berger, Bernlohr, Black, DiRusso, Farber, Guo, Hashimoto, Khodiyar, Kuypers, Maltais, Nebert, Renieri, Schaffer, Stahl, Watkins, Vasiliou, Yamamoto: "Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family." in: Journal of lipid research, Vol. 45, Issue 10, pp. 1958-61, (2004) (PubMed).

Details zu ACSL1

Target: ACSL1 (Acsl1) (Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1))

Andere Bezeichnung: ACSL1 (Acsl1 Produkte)

Hintergrund: The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. [provided by RefSeq].

Molekulargewicht: 77943

NCBI Accession: NP_001986

UniProt: P33121

Pathways: Regulation of Lipid Metabolism by PPARalpha