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AKTIP Antikörper (C-Term)

AKTIP Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB38675 unconjugated
Produktnummer ABIN1881052
  • Target Alle AKTIP Antikörper anzeigen
    AKTIP (AKT Interacting Protein (AKTIP))
    Bindungsspezifität
    • 30
    • 11
    • 7
    • 7
    • 6
    • 2
    • 1
    AA 262-288, C-Term
    Reaktivität
    • 34
    • 31
    • 24
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 58
    • 6
    Kaninchen
    Klonalität
    • 61
    • 3
    Polyklonal
    Konjugat
    • 16
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser AKTIP Antikörper ist unkonjugiert
    Applikation
    • 53
    • 26
    • 26
    • 26
    • 6
    • 6
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Homologie
    C, Pr, M, Rat
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This AKTIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-288 amino acids from the C-terminal region of human AKTIP.
    Klon
    RB38675
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product AKTIP Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Quaye, Dafou, Ramus, Song, Gentry-Maharaj, Maharaj, Notaridou, Hogdall, Kjaer, Christensen, Hogdall, Easton, Jacobs, Menon, Pharoah, Gayther: "Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival." in: Human molecular genetics, Vol. 18, Issue 10, pp. 1869-78, (2009) (PubMed).

    Xu, Sowa, Chen, Li, Gygi, Harper: "An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex." in: Molecular biology of the cell, Vol. 19, Issue 12, pp. 5059-71, (2008) (PubMed).

    Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, (2007) (PubMed).

  • Target
    AKTIP (AKT Interacting Protein (AKTIP))
    Andere Bezeichnung
    AKTIP (AKTIP Produkte)
    Synonyme
    FT1 antikoerper, FTS antikoerper, cb798 antikoerper, fts antikoerper, zgc:77699 antikoerper, fts-A antikoerper, aktip antikoerper, fts-B antikoerper, MGC133931 antikoerper, AL023020 antikoerper, Fif antikoerper, Ft antikoerper, Ft1 antikoerper, Fts antikoerper, AKT interacting protein antikoerper, akt interacting protein antikoerper, AKT interacting protein L homeolog antikoerper, AKT interacting protein S homeolog antikoerper, thymoma viral proto-oncogene 1 interacting protein antikoerper, AKTIP antikoerper, aktip antikoerper, aktip.L antikoerper, aktip.S antikoerper, Aktip antikoerper
    Hintergrund
    The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein.
    Molekulargewicht
    33128
    NCBI Accession
    NP_001012398, NP_071921
    UniProt
    Q9H8T0
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