This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ANXA13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ANXA13.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Reiske, Sui, Ung-Medoff, Donahue, Li, Goldblatt, Li, Kinch: "Identification of annexin A13 as a regulator of chemotherapy resistance using random homozygous gene perturbation." in: Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology, Vol. 32, Issue 2, pp. 61-9, (2010) (PubMed).
Anderson, Polanski, Pieper, Gatlin, Tirumalai, Conrads, Veenstra, Adkins, Pounds, Fagan, Lobley: "The human plasma proteome: a nonredundant list developed by combination of four separate sources." in: Molecular & cellular proteomics : MCP, Vol. 3, Issue 4, pp. 311-26, (2004) (PubMed).
Iglesias, Morgan, Jenkins, Copeland, Gilbert, Fernandez: "Comparative genetics and evolution of annexin A13 as the founder gene of vertebrate annexins." in: Molecular biology and evolution, Vol. 19, Issue 5, pp. 608-18, (2002) (PubMed).
Noda, Okada, Saito, Setou, Xu, Zhang, Hirokawa: "KIFC3, a microtubule minus end-directed motor for the apical transport of annexin XIIIb-associated Triton-insoluble membranes." in: The Journal of cell biology, Vol. 155, Issue 1, pp. 77-88, (2001) (PubMed).
Plant, Lafont, Lecat, Verkade, Simons, Rotin: "Apical membrane targeting of Nedd4 is mediated by an association of its C2 domain with annexin XIIIb." in: The Journal of cell biology, Vol. 149, Issue 7, pp. 1473-84, (2000) (PubMed).
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. The specific function of this gene has not yet been determined, however, it is associated with the plasma membrane of undifferentiated, proliferating endothelial cells and differentiated villus enterocytes. Alternatively spliced transcript variants encoding different isoforms have been identified.