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ATG13 Antikörper (pSer355)

ATG13 Reaktivität: Human DB Wirt: Kaninchen Polyclonal RB40774 unconjugated
Produktnummer ABIN1881081
  • Target Alle ATG13 Antikörper anzeigen
    ATG13 (Autophagy Related 13 (ATG13))
    Bindungsspezifität
    • 15
    • 15
    • 10
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer355
    Reaktivität
    • 55
    • 32
    • 31
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 71
    • 2
    Kaninchen
    Klonalität
    • 71
    • 2
    Polyklonal
    Konjugat
    • 24
    • 9
    • 8
    • 7
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ATG13 Antikörper ist unkonjugiert
    Applikation
    • 52
    • 38
    • 19
    • 13
    • 13
    • 9
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Dot Blot (DB)
    Homologie
    M
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This ATG13 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S355 of human ATG13.
    Klon
    RB40774
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product ATG13 Primärantikörper
  • Applikationshinweise
    DB: 1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Ferreira, Pan-Hammarström, Graham, Gateva, Fontán, Lee, Ortmann, Urcelay, Fernández-Arquero, Núñez, Jorgensen, Ludviksson, Koskinen, Haimila, Clark, Klareskog, Gregersen, Behrens, Hammarström: "Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency." in: Nature genetics, Vol. 42, Issue 9, pp. 777-80, (2010) (PubMed).

    Koh, Lin, Jedd, Wong: "Sirius PSB: a generic system for analysis of biological sequences." in: Journal of bioinformatics and computational biology, Vol. 7, Issue 6, pp. 973-90, (2009) (PubMed).

    Mercer, Kaliappan, Dennis: "A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy." in: Autophagy, Vol. 5, Issue 5, pp. 649-62, (2009) (PubMed).

    Ganley, Lam, Wang, Ding, Chen, Jiang: "ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy." in: The Journal of biological chemistry, Vol. 284, Issue 18, pp. 12297-305, (2009) (PubMed).

    Chan, Longatti, McKnight, Tooze: "Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism." in: Molecular and cellular biology, Vol. 29, Issue 1, pp. 157-71, (2008) (PubMed).

  • Target
    ATG13 (Autophagy Related 13 (ATG13))
    Andere Bezeichnung
    ATG13 (ATG13 Produkte)
    Synonyme
    zgc:63526 antikoerper, KIAA0652 antikoerper, PARATARG8 antikoerper, 1110053A20Rik antikoerper, D2Ertd391e antikoerper, Harbi1 antikoerper, Harbi1l antikoerper, RGD1310685 antikoerper, autophagy related 13 antikoerper, ATG13 autophagy related 13 homolog (S. cerevisiae) antikoerper, ATG13 antikoerper, atg13 antikoerper, Atg13 antikoerper
    Hintergrund
    Autophagy factor required for autophagosome formation. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex.
    Molekulargewicht
    56572
    NCBI Accession
    NP_001136145, NP_001192048, NP_001192049, NP_001192050, NP_001192051, NP_055556
    UniProt
    O75143
    Pathways
    PI3K-Akt Signalweg, Autophagie
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