This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ATP8B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-84 amino acids from the N-terminal region of human ATP8B3.
ATP8B3
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
HRP
Applikationshinweise
WB: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Scott, Muglia, Kong, Guan, Flickinger, Upmanyu, Tozzi, Li, Burmeister, Absher, Thompson, Francks, Meng, Antoniades, Southwick, Schatzberg, Bunney, Barchas, Jones, Day, Matthews, McGuffin et al.: "Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry...." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 18, pp. 7501-6, (2009) (PubMed).
Harris, Arias: "FIC1, a P-type ATPase linked to cholestatic liver disease, has homologues (ATP8B2 and ATP8B3) expressed throughout the body." in: Biochimica et biophysica acta, Vol. 1633, Issue 2, pp. 127-31, (2003) (PubMed).
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another. This gene encodes the member 3 of the phospholipid-transporting ATPase 8B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].