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BCL9L Antikörper (N-Term)

BCL9L Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB41624 unconjugated
Produktnummer ABIN1881110
  • Target Alle BCL9L Antikörper anzeigen
    BCL9L (B-Cell CLL/lymphoma 9-Like (BCL9L))
    Bindungsspezifität
    • 12
    • 9
    • 7
    • 1
    • 1
    • 1
    • 1
    AA 147-176, N-Term
    Reaktivität
    • 27
    • 4
    • 4
    Human
    Wirt
    • 26
    • 1
    Kaninchen
    Klonalität
    • 26
    • 1
    Polyklonal
    Konjugat
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BCL9L Antikörper ist unkonjugiert
    Applikation
    • 20
    • 17
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This BCL9L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-176 amino acids from the N-terminal region of human BCL9L.
    Klon
    RB41624
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product BCL9L Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Miller, Rutherford, Johnson, Fiedler, Bienz: "Allosteric remodelling of the histone H3 binding pocket in the Pygo2 PHD finger triggered by its binding to the B9L/BCL9 co-factor." in: Journal of molecular biology, Vol. 401, Issue 5, pp. 969-84, (2010) (PubMed).

    Fritzmann, Morkel, Besser, Budczies, Kosel, Brembeck, Stein, Fichtner, Schlag, Birchmeier: "A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential." in: Gastroenterology, Vol. 137, Issue 1, pp. 165-75, (2009) (PubMed).

    Sampietro, Dahlberg, Cho, Hinds, Kimelman, Xu: "Crystal structure of a beta-catenin/BCL9/Tcf4 complex." in: Molecular cell, Vol. 24, Issue 2, pp. 293-300, (2006) (PubMed).

    Brembeck, Schwarz-Romond, Bakkers, Wilhelm, Hammerschmidt, Birchmeier: "Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions." in: Genes & development, Vol. 18, Issue 18, pp. 2225-30, (2004) (PubMed).

  • Target
    BCL9L (B-Cell CLL/lymphoma 9-Like (BCL9L))
    Andere Bezeichnung
    BCL9L (BCL9L Produkte)
    Synonyme
    BCL9-2 antikoerper, DLNB11 antikoerper, B9L antikoerper, BC003321 antikoerper, bcl9-2 antikoerper, BCL9L antikoerper, B-cell CLL/lymphoma 9 like antikoerper, B cell CLL/lymphoma 9-like antikoerper, B-cell CLL/lymphoma 9-like antikoerper, BCL9L antikoerper, Bcl9l antikoerper, bcl9l antikoerper
    Hintergrund
    Transcriptional regulator that acts as an activator. Promotes beta-catenin transcriptional activity. Plays a role in tumorigenesis. Enhances the neoplastic transforming activity of CTNNB1 (By similarity).
    Molekulargewicht
    157129
    NCBI Accession
    NP_872363
    UniProt
    Q86UU0
    Pathways
    Stem Cell Maintenance
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