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BLMH Antikörper (AA 212-242)

BLMH Reaktivität: Human, Ratte, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1881113
  • Target Alle BLMH Antikörper anzeigen
    BLMH (Bleomycin Hydrolase (BLMH))
    Bindungsspezifität
    • 15
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 212-242
    Reaktivität
    • 28
    • 27
    • 21
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 40
    • 11
    • 1
    Kaninchen
    Klonalität
    • 44
    • 8
    Polyklonal
    Konjugat
    • 24
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BLMH Antikörper ist unkonjugiert
    Applikation
    • 45
    • 13
    • 13
    • 12
    • 9
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Rb
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This BLMH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-242 amino acids from the Central region of human BLMH.
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:25
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Ferrando, Velasco, Campo, Lopez-Otin: "Cloning and expression analysis of human bleomycin hydrolase, a cysteine proteinase involved in chemotherapy resistance." in: Cancer research, Vol. 56, Issue 8, pp. 1746-50, (1996) (PubMed).

    Brömme, Rossi, Smeekens, Anderson, Payan: "Human bleomycin hydrolase: molecular cloning, sequencing, functional expression, and enzymatic characterization." in: Biochemistry, Vol. 35, Issue 21, pp. 6706-14, (1996) (PubMed).

  • Target
    BLMH (Bleomycin Hydrolase (BLMH))
    Andere Bezeichnung
    BLMH (BLMH Produkte)
    Hintergrund
    The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity (By similarity).
    Molekulargewicht
    52562
    NCBI Accession
    NP_000377
    UniProt
    Q13867
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