Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

BRMS1 Antikörper (N-Term)

BRMS1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB40250 unconjugated
Produktnummer ABIN1881120
  • Target Alle BRMS1 Antikörper anzeigen
    BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
    Bindungsspezifität
    • 15
    • 7
    • 7
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 48-77, N-Term
    Reaktivität
    • 53
    • 25
    • 24
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 51
    • 2
    Kaninchen
    Klonalität
    • 51
    • 2
    Polyklonal
    Konjugat
    • 22
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BRMS1 Antikörper ist unkonjugiert
    Applikation
    • 46
    • 22
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Homologie
    M, Rat
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This BRMS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-77 amino acids from the N-terminal region of human BRMS1.
    Klon
    RB40250
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product BRMS1 Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Wu, McEwen, Harihar, Baker, DeWald, Zhou: "BRMS1 expression alters the ultrastructural, biomechanical and biochemical properties of MDA-MB-435 human breast carcinoma cells: an AFM and Raman microspectroscopy study." in: Cancer letters, Vol. 293, Issue 1, pp. 82-91, (2010) (PubMed).

    Vaidya, Sanchez, Kim, Welch: "Expression of the Breast Cancer Metastasis Suppressor 1 (BRMS1) maintains in vitro chemosensitivity of breast cancer cells." in: Cancer letters, Vol. 281, Issue 1, pp. 100-7, (2009) (PubMed).

    Frolova, Edmonds, Bodenstine, Seitz, Johnson, Feng, Welch, Frost: "A shift from nuclear to cytoplasmic breast cancer metastasis suppressor 1 expression is associated with highly proliferative estrogen receptor-negative breast cancers." in: Tumour biology, Vol. 30, Issue 3, pp. 148-59, (2009) (PubMed).

    Cicek, Fukuyama, Cicek, Sizemore, Welch, Sizemore, Casey: "BRMS1 contributes to the negative regulation of uPA gene expression through recruitment of HDAC1 to the NF-kappaB binding site of the uPA promoter." in: Clinical & experimental metastasis, Vol. 26, Issue 3, pp. 229-37, (2009) (PubMed).

  • Target
    BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
    Andere Bezeichnung
    BRMS1 (BRMS1 Produkte)
    Synonyme
    MGC98869 antikoerper, BRMS1 antikoerper, BRMS1L antikoerper, AV003220 antikoerper, AW554636 antikoerper, si:zc188c22.3 antikoerper, si:zc194c5.2 antikoerper, wu:fb57b08 antikoerper, zgc:56414 antikoerper, breast cancer metastasis suppressor 1 antikoerper, breast cancer metastasis-suppressor 1 antikoerper, breast cancer metastasis suppressor 1 L homeolog antikoerper, BRMS1 antikoerper, Brms1 antikoerper, brms1.L antikoerper, brms1 antikoerper
    Hintergrund
    This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.
    Molekulargewicht
    28461
    NCBI Accession
    NP_056214
    UniProt
    Q9HCU9
Sie sind hier:
Kundenservice