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CBS Antikörper (N-Term)

CBS Reaktivität: Human, Maus WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB22961 unconjugated
Produktnummer ABIN1881141
  • Target Alle CBS Antikörper anzeigen
    CBS (Cystathionine-beta-Synthase (CBS))
    Bindungsspezifität
    • 15
    • 9
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 104-133, N-Term
    Reaktivität
    • 54
    • 40
    • 12
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 65
    • 9
    Kaninchen
    Klonalität
    • 59
    • 15
    Polyklonal
    Konjugat
    • 39
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CBS Antikörper ist unkonjugiert
    Applikation
    • 56
    • 31
    • 17
    • 14
    • 14
    • 13
    • 13
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This CBS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the N-terminal region of human CBS.
    Klon
    RB22961
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product CBS Primärantikörper
  • Applikationshinweise
    IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Lee, Feliers, Mariappan, Sataranatarajan, Choudhury, Gorin, Kasinath: "Tadalafil Integrates Nitric Oxide-Hydrogen Sulfide Signaling to Inhibit High Glucose-induced Matrix Protein Synthesis in Podocytes." in: The Journal of biological chemistry, Vol. 290, Issue 19, pp. 12014-26, (2015) (PubMed).

    Lee, Mariappan, Feliers, Cavaglieri, Sataranatarajan, Abboud, Choudhury, Kasinath: "Hydrogen sulfide inhibits high glucose-induced matrix protein synthesis by activating AMP-activated protein kinase in renal epithelial cells." in: The Journal of biological chemistry, Vol. 287, Issue 7, pp. 4451-61, (2012) (PubMed).

  • Target
    CBS (Cystathionine-beta-Synthase (CBS))
    Andere Bezeichnung
    CBS (CBS Produkte)
    Synonyme
    hip4 antikoerper, GB12529 antikoerper, CBS antikoerper, DDBDRAFT_0189727 antikoerper, DDBDRAFT_0191292 antikoerper, DDB_0189727 antikoerper, DDB_0191292 antikoerper, cbs antikoerper, AI047524 antikoerper, AI303044 antikoerper, HIP4 antikoerper, cb442 antikoerper, wu:fb37g05 antikoerper, wu:fm61c07 antikoerper, wu:fq06c06 antikoerper, zgc:113704 antikoerper, cystathionine-beta-synthase L homeolog antikoerper, cystathionine-beta-synthase antikoerper, cystathionine beta-synthase antikoerper, cystathionine beta-synthase CBS antikoerper, cystathionine beta synthase antikoerper, cystathionine-beta-synthase S homeolog antikoerper, cystathionine-beta-synthase b antikoerper, cbs.L antikoerper, cbs antikoerper, Cbs antikoerper, CBS antikoerper, CNA06170 antikoerper, Tb11.02.5400 antikoerper, cysB antikoerper, LOC100635325 antikoerper, cbs.S antikoerper, cbsb antikoerper
    Hintergrund
    CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. This protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria.
    Molekulargewicht
    60587
    NCBI Accession
    NP_000062, NP_001171479, NP_001171480
    UniProt
    P35520
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