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CBS Antikörper (N-Term)

Name: CBS Antikörper (N-Term)
SKU: ABIN1881141
Price: 467.5 EUR
Availability: InStock

CBS Reaktivität: Human, Maus WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB22961 unconjugated

Western blot analysis of CBS Antibody (N-term) (ABIN1881141 and ABIN2841140) in mouse kidney tissue and Ramos cell line lysates (35 μg/lane). (CBS Antikörper (N-Term))

Confocal immunofluorescent analysis of CBS Antibody (N-term) (ABIN1881141 and ABIN2841140) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (CBS Antikörper (N-Term))

Western blot analysis of CBS (arrow) using rabbit polyclonal CBS Antibody (N-term) (ABIN1881141 and ABIN2841140). (CBS Antikörper (N-Term))

CBS Antibody (N-term) (ABIN1881141 and ABIN2841140) flow cytometric analysis of Ramos cells (bottom histogram) compared to a negative control cell (top histogram). (CBS Antikörper (N-Term))

FACS

CBS Antibody (N-term) (ABIN1881141 and ABIN2841140) IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. (CBS Antikörper (N-Term))

IHC (p)

5 Abbildungen

(2 Referenzen)

Produktnummer ABIN1881141

Datenblatt (PDF)

Target Alle CBS Antikörper anzeigen

CBS (Cystathionine-beta-Synthase (CBS))
Bindungsspezifität
15

9

6

6

4

4

2

2

2

2

1

1

1

1

1
AA 104-133, N-Term
Reaktivität
53

40

12

4

2

2

2

2

1

1

1

1

1
Human, Maus
Wirt
64

9
Kaninchen
Passende Sekundärantikörper
Klonalität
58

15
Polyklonal
Konjugat
38

6

6

4

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CBS Antikörper ist unkonjugiert
Applikation
55

31

16

14

13

13

13

7

5

5

3

2

2

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This CBS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the N-terminal region of human CBS.

Klon

RB22961

Isotyp

Ig Fraction

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CBS Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 6A9 unconjugated

anti-Cystathionine-beta-Synthase (CBS) (N-Term) antibody
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CBS Reaktivität: Human WB, ELISA, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated

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KO Validated CBS Reaktivität: Human WB, IF, IHC (p), IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) antibody
CBS Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Monoclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 1-551) antibody
CBS Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 1-551) antibody
CBS Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Haltbarkeit

6 months
Lee, Feliers, Mariappan, Sataranatarajan, Choudhury, Gorin, Kasinath: "Tadalafil Integrates Nitric Oxide-Hydrogen Sulfide Signaling to Inhibit High Glucose-induced Matrix Protein Synthesis in Podocytes." in: The Journal of biological chemistry, Vol. 290, Issue 19, pp. 12014-26, (2015) (PubMed).

Lee, Mariappan, Feliers, Cavaglieri, Sataranatarajan, Abboud, Choudhury, Kasinath: "Hydrogen sulfide inhibits high glucose-induced matrix protein synthesis by activating AMP-activated protein kinase in renal epithelial cells." in: The Journal of biological chemistry, Vol. 287, Issue 7, pp. 4451-61, (2012) (PubMed).
Target

CBS (Cystathionine-beta-Synthase (CBS))

Andere Bezeichnung

CBS (CBS Produkte)

Hintergrund

CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. This protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria.

Molekulargewicht

60587

NCBI Accession

NP_000062, NP_001171479, NP_001171480

UniProt

P35520