Cyclin B1 Antikörper (pSer35)
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- Target Alle Cyclin B1 (CCNB1) Antikörper anzeigen
- Cyclin B1 (CCNB1)
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Bindungsspezifität
- pSer35
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Cyclin B1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Dot Blot (DB)
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This CCNB1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S35 of human CCNB1.
- Klon
- RB42141
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product CCNB1 Primärantikörper
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- Applikationshinweise
- WB: 1:1100. DB: 1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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Restoration of the tumor suppressor p53 by downregulating cyclin B1 in human papillomavirus 16/18-infected cancer cells." in: Oncogene, Vol. 29, Issue 41, pp. 5591-603, (2010) (PubMed).
: "The APC/C recruits cyclin B1-Cdk1-Cks in prometaphase before D box recognition to control mitotic exit." in: The Journal of cell biology, Vol. 190, Issue 4, pp. 587-602, (2010) (PubMed).
: "Phosphorylation of Mcl-1 by CDK1-cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest." in: The EMBO journal, Vol. 29, Issue 14, pp. 2407-20, (2010) (PubMed).
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Restoration of the tumor suppressor p53 by downregulating cyclin B1 in human papillomavirus 16/18-infected cancer cells." in: Oncogene, Vol. 29, Issue 41, pp. 5591-603, (2010) (PubMed).
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- Target
- Cyclin B1 (CCNB1)
- Andere Bezeichnung
- CCNB1 (CCNB1 Produkte)
- Synonyme
- ccnb antikoerper, cycb antikoerper, cb267 antikoerper, cycb1 antikoerper, wu:fa19g04 antikoerper, wu:fb16d01 antikoerper, wu:fb16e07 antikoerper, wu:fi21c01 antikoerper, ccnb1 antikoerper, MGC53596 antikoerper, CCNB antikoerper, Ccnb1-rs1 antikoerper, Ccnb1-rs13 antikoerper, CycB1 antikoerper, Cycb-4 antikoerper, Cycb-5 antikoerper, Cycb1-rs1 antikoerper, cyclin B1 antikoerper, cyclin B1 S homeolog antikoerper, ccnb1 antikoerper, ccnb1.2 antikoerper, ccnb1.S antikoerper, CCNB1 antikoerper, Ccnb1 antikoerper, ccnb1.2.S antikoerper
- Hintergrund
- The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq].
- Molekulargewicht
- 48337
- NCBI Accession
- NP_114172
- UniProt
- P14635
- Pathways
- Zellzyklus, AMPK Signaling, Mitotic G1-G1/S Phases, M Phase
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