Cyclin B3 Antikörper (pThr280)
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- Target Alle Cyclin B3 (CCNB3) Antikörper anzeigen
- Cyclin B3 (CCNB3)
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Bindungsspezifität
- pThr280
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Cyclin B3 Antikörper ist unkonjugiert
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Applikation
- Dot Blot (DB)
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This CCNB3 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T280 of human CCNB3.
- Klon
- RB42155
- Isotyp
- Ig Fraction
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- Applikationshinweise
- DB: 1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution." in: Science (New York, N.Y.), Vol. 308, Issue 5725, pp. 1149-54, (2005) (PubMed).
: "Hypophosphorylation of poly(A) polymerase and increased polyadenylation activity are associated with human immunodeficiency virus type 1 Vpr expression." in: Virology, Vol. 292, Issue 2, pp. 321-30, (2002) (PubMed).
: "Characterization and expression of mammalian cyclin b3, a prepachytene meiotic cyclin." in: The Journal of biological chemistry, Vol. 277, Issue 44, pp. 41960-9, (2002) (PubMed).
: "
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Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution." in: Science (New York, N.Y.), Vol. 308, Issue 5725, pp. 1149-54, (2005) (PubMed).
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- Target
- Cyclin B3 (CCNB3)
- Andere Bezeichnung
- CCNB3 (CCNB3 Produkte)
- Hintergrund
- The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Studies of similar genes in chick and Drosophila suggest that this cyclin may associate with CDC2 and CDK2 kinases, and be required for proper spindle reorganization and restoration of the interphase nucleus. Two transcript variants encoding different isoforms have been found for this gene.
- Molekulargewicht
- 157916
- NCBI Accession
- NP_149020, NP_391990
- UniProt
- Q8WWL7
- Pathways
- Zellzyklus, Chromatin Binding
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