This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This COLQ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-353 amino acids from the C-terminal region of human COLQ.
EAD antikoerper, A130034K24Rik antikoerper, collagen like tail subunit of asymmetric acetylcholinesterase antikoerper, collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase antikoerper, COLQ antikoerper, Colq antikoerper
Hintergrund
This gene encodes the subunit of a collagen-like molecule associated with acetylcholinesterase in skeletal muscle. Each molecule is composed of three identical subunits. Each subunit contains a proline-rich attachment domain (PRAD) that binds an acetylcholinesterase tetramer to anchor the catalytic subunit of the enzyme to the basal lamina. Mutations in this gene are associated with endplate acetylcholinesterase deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.