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CREB3 Antikörper (N-Term)

CREB3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB42213 unconjugated
Produktnummer ABIN1881228
  • Target Alle CREB3 Antikörper anzeigen
    CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))
    Bindungsspezifität
    • 12
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 66-94, N-Term
    Reaktivität
    • 40
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 36
    • 3
    • 1
    Kaninchen
    Klonalität
    • 37
    • 3
    Polyklonal
    Konjugat
    • 23
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CREB3 Antikörper ist unkonjugiert
    Applikation
    • 31
    • 18
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This CREB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the N-terminal region of human CREB3.
    Klon
    RB42213
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product CREB3 Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Kim, Choi, Choi, Kang, Kim, Lee, Lee, Lee, Kim, Jun, Jeong, Yoon: "HDAC3 selectively represses CREB3-mediated transcription and migration of metastatic breast cancer cells." in: Cellular and molecular life sciences : CMLS, Vol. 67, Issue 20, pp. 3499-510, (2010) (PubMed).

    Audas, Li, Liang, Lu: "A novel protein, Luman/CREB3 recruitment factor, inhibits Luman activation of the unfolded protein response." in: Molecular and cellular biology, Vol. 28, Issue 12, pp. 3952-66, (2008) (PubMed).

  • Target
    CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))
    Andere Bezeichnung
    CREB3 (CREB3 Produkte)
    Synonyme
    LUMAN antikoerper, LZIP antikoerper, AU044960 antikoerper, AW538053 antikoerper, C80076 antikoerper, LZIP-1 antikoerper, LZIP-2 antikoerper, Luman antikoerper, creb3 antikoerper, luman antikoerper, lzip antikoerper, cAMP responsive element binding protein 3 antikoerper, cAMP responsive element binding protein 3 S homeolog antikoerper, CREB3 antikoerper, Creb3 antikoerper, creb3.S antikoerper
    Hintergrund
    This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.
    Molekulargewicht
    41379
    NCBI Accession
    NP_006359
    UniProt
    O43889
    Pathways
    Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Maintenance of Protein Location, Unfolded Protein Response
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