DIRC2 Antikörper (AA 202-229)

Produktnummer ABIN1881261

Produktdetails anti-DIRC2 Antikörper

Target: DIRC2 (Disrupted in Renal Carcinoma 2 (DIRC2))

Bindungsspezifität: AA 202-229

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DIRC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DIRC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-229 amino acids from the Central region of human DIRC2.

Klon: RB42515

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-DIRC2 Antikörper (ABIN1881261)

Bodmer, Eleveld, Kater-Baats, Janssen, Janssen, Weterman, Schoenmakers, Nickerson, Linehan, Zbar, van Kessel: "Disruption of a novel MFS transporter gene, DIRC2, by a familial renal cell carcinoma-associated t(2;3)(q35;q21)." in: Human molecular genetics, Vol. 11, Issue 6, pp. 641-9, (2002) (PubMed).

Bodmer, Janssen, Jonkers, van den Berg, Dijkhuizen, Debiec-Rychter, Schoenmakers, van Kessel: "Molecular cytogenetic analysis of clustered sporadic and familial renal cell carcinoma-associated 3q13 approximately q22 breakpoints." in: Cancer genetics and cytogenetics, Vol. 136, Issue 2, pp. 95-100, (2002) (PubMed).

Details zu DIRC2

Target: DIRC2 (Disrupted in Renal Carcinoma 2 (DIRC2))

Andere Bezeichnung: DIRC2 (DIRC2 Produkte)

Synonyme: MGC80843 antikoerper, zgc:92095 antikoerper, rcc4 antikoerper, MGC69320 antikoerper, RCC4 antikoerper, disrupted in renal carcinoma 2 antikoerper, disrupted in renal carcinoma 2 L homeolog antikoerper, disrupted in renal carcinoma 2 (human) antikoerper, DIRC2 antikoerper, dirc2.L antikoerper, dirc2 antikoerper, Dirc2 antikoerper

Hintergrund: This gene encodes a membrane-bound protein from the major facilitator superfamily of transporters. Disruption of this gene by translocation has been associated with haplo-insufficiency and renal cell carcinomas. Alternatively spliced transcript variants have been described, but their biological validity has not yet been determined.

Molekulargewicht: 52088

NCBI Accession: NP_116228

UniProt: Q96SL1