ECE2 Antikörper (AA 551-579)

Produktnummer ABIN1881279

Produktdetails anti-ECE2 Antikörper

Target: ECE2 (Endothelin Converting Enzyme 2 (ECE2))

Bindungsspezifität: AA 551-579

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ECE2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: B, M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ECE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 551-579 amino acids from the Central region of human ECE2.

Klon: RB43866

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-ECE2 Antikörper (ABIN1881279)

Muzny, Scherer, Kaul, Wang, Yu, Sudbrak, Buhay, Chen, Cree, Ding, Dugan-Rocha, Gill, Gunaratne, Harris, Hawes, Hernandez, Hodgson, Hume, Jackson, Khan, Kovar-Smith, Lewis, Lozado, Metzker et al.: "The DNA sequence, annotation and analysis of human chromosome 3. ..." in: Nature, Vol. 440, Issue 7088, pp. 1194-8, (2006) (PubMed).

Lorenzo, Khan, Wang, Tai, Chan, Cheung, Marsden: "Human endothelin converting enzyme-2 (ECE2): characterization of mRNA species and chromosomal localization." in: Biochimica et biophysica acta, Vol. 1522, Issue 1, pp. 46-52, (2001) (PubMed).

Nagase, Ishikawa, Miyajima, Tanaka, Kotani, Nomura, Ohara: "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 5, Issue 1, pp. 31-9, (1998) (PubMed).

Details zu ECE2

Target: ECE2 (Endothelin Converting Enzyme 2 (ECE2))

Andere Bezeichnung: ECE2 (ECE2 Produkte)

Synonyme: ECE2 antikoerper, 1810009K13Rik antikoerper, 6330509A19Rik antikoerper, 9630025D12Rik antikoerper, BB127715 antikoerper, endothelin converting enzyme 2 antikoerper, endothelin-converting enzyme 2 antikoerper, ECE2 antikoerper, LOC702851 antikoerper, ece2 antikoerper, LOC100543478 antikoerper, Ece2 antikoerper

Hintergrund: Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity.

NCBI Accession: NP_001032401, NP_001093590, NP_001093591, NP_055508, NP_115707

UniProt: O60344

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling