eIF4EBP2 Antikörper (C-Term)

Produktnummer ABIN1881292

Produktdetails anti-eIF4EBP2 Antikörper

Target: eIF4EBP2 (EIF4EBP2) (Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2))

Bindungsspezifität: AA 87-115, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser eIF4EBP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This EIF4EBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-115 amino acids from the C-terminal region of human EIF4EBP2.

Klon: RB41859

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-eIF4EBP2 Antikörper (ABIN1881292)

Bidinosti, Martineau, Frank, Sonenberg: "Repair of isoaspartate formation modulates the interaction of deamidated 4E-BP2 with mTORC1 in brain." in: The Journal of biological chemistry, Vol. 285, Issue 25, pp. 19402-8, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Gingras, Sonenberg: "Adenovirus infection inactivates the translational inhibitors 4E-BP1 and 4E-BP2." in: Virology, Vol. 237, Issue 1, pp. 182-6, (1997) (PubMed).

Details zu eIF4EBP2

Target: eIF4EBP2 (EIF4EBP2) (Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2))

Andere Bezeichnung: EIF4EBP2 (EIF4EBP2 Produkte)

Synonyme: 4ebp2 antikoerper, MGC75579 antikoerper, wu:fa55e11 antikoerper, wu:fp45e09 antikoerper, MGC78987 antikoerper, EIF4EBP2 antikoerper, eIF-4E antikoerper, Tb06.28P18.1010 antikoerper, 4EBP2 antikoerper, PHASII antikoerper, 2810011I19Rik antikoerper, 4E-BP2 antikoerper, AA792569 antikoerper, BC010348 antikoerper, PHAS-II antikoerper, eukaryotic translation initiation factor 4E binding protein 2 antikoerper, eukaryotic translation initiation factor 4E binding protein 2 L homeolog antikoerper, eukaryotic initiation factor 4E antikoerper, eukaryotic translation initiation factor 4E antikoerper, putative eukaryotic translation initiation factor 4e antikoerper, eif4ebp2 antikoerper, Eif4ebp2 antikoerper, eif4ebp2.L antikoerper, EIF4EBP2 antikoerper, eIF-4E antikoerper, Tb927.6.1870 antikoerper, LMJF_30_0450 antikoerper

Hintergrund: This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection.

Molekulargewicht: 12939

NCBI Accession: NP_004087

UniProt: Q13542