ENPP3 Antikörper (C-Term)

Produktnummer ABIN1881297

Produktdetails anti-ENPP3 Antikörper

Target: ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))

Bindungsspezifität: AA 814-843, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ENPP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ENPP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 814-843 amino acids from the C-terminal region of human ENPP3.

Klon: RB24586

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-ENPP3 Antikörper (ABIN1881297)

Ono, Taniguchi, Higashi, Mita, Kajiwara, Yamaguchi, Tatsuno, Fukutomi, Tanimoto, Sekiya, Oshikata, Tsuburai, Tsurikisawa, Otomo, Maeda, Hasegawa, Miyazaki, Kumamoto, Akiyama: "CD203c expression on human basophils is associated with asthma exacerbation." in: The Journal of allergy and clinical immunology, Vol. 125, Issue 2, pp. 483-489.e3, (2010) (PubMed).

Wolanczyk-Medrala, Barg, Gogolewski, Panaszek, Liebhart, Litwa, Medrala: "Influence of hyperosmotic conditions on basophil CD203c upregulation in patients with food-dependent exercise-induced anaphylaxis." in: Annals of agricultural and environmental medicine : AAEM, Vol. 16, Issue 2, pp. 301-4, (2010) (PubMed).

Chirumbolo, Brizzi, Ortolani, Vella, Bellavite: "Inhibition of CD203c membrane up-regulation in human basophils by high dilutions of histamine: a controlled replication study." in: Inflammation research : official journal of the European Histamine Research Society ... [et al.], Vol. 58, Issue 11, pp. 755-64, (2009) (PubMed).

Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).

Details zu ENPP3

Target: ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))

Andere Bezeichnung: ENPP3 (ENPP3 Produkte)

Synonyme: B10 antikoerper, CD203c antikoerper, NPP3 antikoerper, PD-IBETA antikoerper, PDNP3 antikoerper, Npp3 antikoerper, RB13-6 antikoerper, AI876438 antikoerper, ENPP3 antikoerper, ectonucleotide pyrophosphatase/phosphodiesterase 3 antikoerper, ectonucleotide pyrophosphatase/phosphodiesterase 3 L homeolog antikoerper, ENPP3 antikoerper, Enpp3 antikoerper, enpp3 antikoerper, enpp3.L antikoerper

Hintergrund: The protein encoded by this gene belongs to a series of ectoenzymes that are involved in hydrolysis of extracellular nucleotides. These ectoenzymes possess ATPase and ATP pyrophosphatase activities and are type II transmembrane proteins. Expression of the related rat mRNA has been found in a subset of immature glial cells and in the alimentary tract. The corresponding rat protein has been detected in the pancreas, small intestine, colon, and liver. The human mRNA is expressed in glioma cells, prostate, and uterus. Expression of the human protein has been detected in uterus, basophils, and mast cells. [provided by RefSeq].

Molekulargewicht: 100124

NCBI Accession: NP_005012

UniProt: O14638

Pathways: Regulation of Muscle Cell Differentiation, Negative Regulation of Transporter Activity