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FAP Antikörper (N-Term)

FAP Reaktivität: Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB40867 unconjugated
Produktnummer ABIN1881337
  • Target Alle FAP Antikörper anzeigen
    FAP (Fibroblast Activation Protein, alpha (FAP))
    Bindungsspezifität
    • 16
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 15-41, N-Term
    Reaktivität
    • 66
    • 31
    • 21
    • 13
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 62
    • 11
    Kaninchen
    Klonalität
    • 61
    • 12
    Polyklonal
    Konjugat
    • 42
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FAP Antikörper ist unkonjugiert
    Applikation
    • 57
    • 24
    • 18
    • 13
    • 13
    • 11
    • 10
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Mouse Fap antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-41 amino acids from the N-terminal region of mouse Fap.
    Klon
    RB40867
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product FAP Primärantikörper
  • Applikationshinweise
    WB: 1:2000. WB: 1:500. IHC-P: 1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Wen, Wang, Ma, Li, Zhou, Mu, Leng, Shi, Li, Wei: "Immunotherapy targeting fibroblast activation protein inhibits tumor growth and increases survival in a murine colon cancer model." in: Cancer science, Vol. 101, Issue 11, pp. 2325-32, (2010) (PubMed).

    Santos, Jung, Aziz, Kissil, Puré: "Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice." in: The Journal of clinical investigation, Vol. 119, Issue 12, pp. 3613-25, (2009) (PubMed).

    Kennedy, Dong, Chen, Chen: "Elevation of seprase expression and promotion of an invasive phenotype by collagenous matrices in ovarian tumor cells." in: International journal of cancer. Journal international du cancer, Vol. 124, Issue 1, pp. 27-35, (2008) (PubMed).

  • Target
    FAP (Fibroblast Activation Protein, alpha (FAP))
    Andere Bezeichnung
    Fap (FAP Produkte)
    Synonyme
    fap-A antikoerper, gene 13 antikoerper, FAP antikoerper, fapa antikoerper, dppiv antikoerper, seprase antikoerper, DPPIV antikoerper, FAPA antikoerper, fibroblast activation protein antikoerper, fibroblast activation protein alpha L homeolog antikoerper, fibroblast activation protein alpha antikoerper, fibroblast activation protein, alpha antikoerper, prolyl endopeptidase FAP antikoerper, Fap antikoerper, fap.L antikoerper, FAP antikoerper, fap antikoerper, LOC100547273 antikoerper
    Hintergrund
    In association with DPP4 is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM (By similarity). May have a role in tissue remodeling during development and wound healing, and contribute to invasiveness in malignant cancers.
    Molekulargewicht
    87945
    NCBI Accession
    NP_032012
    UniProt
    P97321
    Pathways
    Tube Formation
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