FMO5 Antikörper (C-Term)

Produktnummer ABIN1881348

Produktdetails anti-FMO5 Antikörper

Target: FMO5 (Flavin Containing Monooxygenase 5 (FMO5))

Bindungsspezifität: AA 474-502, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FMO5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FMO5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-502 amino acids from the C-terminal region of human FMO5.

Klon: RB42789

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-FMO5 Antikörper (ABIN1881348)

Ross, Katzov-Eckert, Dubé, Brooks, Rassekh, Barhdadi, Feroz-Zada, Visscher, Brown, Rieder, Rogers, Phillips, Carleton, Hayden: "Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy." in: Nature genetics, Vol. 41, Issue 12, pp. 1345-9, (2009) (PubMed).

Furnes, Feng, Sommer, Schlenk: "Identification of novel variants of the flavin-containing monooxygenase gene family in African Americans." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 31, Issue 2, pp. 187-93, (2003) (PubMed).

Details zu FMO5

Target: FMO5 (Flavin Containing Monooxygenase 5 (FMO5))

Andere Bezeichnung: FMO5 (FMO5 Produkte)

Synonyme: MGC68633 antikoerper, MGC108355 antikoerper, sb:cb1007 antikoerper, wu:fc05b01 antikoerper, wu:fk47g04 antikoerper, 5033418D19Rik antikoerper, AI195026 antikoerper, flavin containing monooxygenase 5 S homeolog antikoerper, flavin containing monooxygenase 5 antikoerper, fmo5.S antikoerper, fmo5 antikoerper, MCYG_00559 antikoerper, FMO5 antikoerper, Fmo5 antikoerper

Hintergrund: Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 60221

NCBI Accession: NP_001138301, NP_001138302, NP_001452

UniProt: P49326