This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This FOXK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 684-710 amino acids from the C-terminal region of human FOXK1.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Tsai, Huang, Chang, Sun, Chuang, Hsiao: "Crystal structure of the human FOXK1a-DNA complex and its implications on the diverse binding specificity of winged helix/forkhead proteins." in: The Journal of biological chemistry, Vol. 281, Issue 25, pp. 17400-9, (2006) (PubMed).
Huang, Lee: "Identification and characterization of a novel human FOXK1 gene in silico." in: International journal of oncology, Vol. 25, Issue 3, pp. 751-7, (2004) (PubMed).
Katoh, Katoh: "Identification and characterization of human FOXK1 gene in silico." in: International journal of molecular medicine, Vol. 14, Issue 1, pp. 127-32, (2004) (PubMed).
FOXK1 is a transcriptional activator that binds to the upstream enhancer region (CCAC box) of myoglobin gene. It plays a role in myogenic differentiation and in remodeling processes of adult muscles that occur in response to physiological stimuli.