This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This Rat Ggt1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-39 amino acids from the N-terminal region of rat Ggt1.
GGT1
Reaktivität: Human
WB, IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
WB: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Aly, Lightfoot, El-Shemy: "Modulatory role of lipoic acid on lipopolysaccharide-induced oxidative stress in adult rat Sertoli cells in vitro." in: Chemico-biological interactions, Vol. 182, Issue 2-3, pp. 112-8, (2009) (PubMed).
Hamden, Carreau, Ellouz, Masmoudi, El: "Protective effect of 17beta-estradiol on oxidative stress and liver dysfunction in aged male rats." in: Journal of physiology and biochemistry, Vol. 63, Issue 3, pp. 195-201, (2008) (PubMed).
Pandur, Pankiv, Johannessen, Moens, Huseby: "Gamma-glutamyltransferase is upregulated after oxidative stress through the Ras signal transduction pathway in rat colon carcinoma cells." in: Free radical research, Vol. 41, Issue 12, pp. 1376-84, (2007) (PubMed).
Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracelular GSH level. It is part of the cell antioxidant defense mechanism. Catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors. Alternatively, glutathione can be hydrolyzed to give Cys-Gly and gamma glutamate.