This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This GGT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-152 amino acids from the N-terminal region of human GGT1.
GGT1
Reaktivität: Human
ELISA, IHC, IF
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
WB: 1:1000. WB: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Ikeda, Maki, Yin, Kawate, Adachi, Ohnaka, Takayanagi, Kono: "Relation of coffee consumption and serum liver enzymes in Japanese men and women with reference to effect modification of alcohol use and body mass index." in: Scandinavian journal of clinical and laboratory investigation, Vol. 70, Issue 3, pp. 171-9, (2010) (PubMed).
Fujita, Ueno, Hata: "Association of gamma-glutamyltransferase with incidence of type 2 diabetes in Japan." in: Experimental biology and medicine (Maywood, N.J.), Vol. 235, Issue 3, pp. 335-41, (2010) (PubMed).
Speliotes, Butler, Palmer, Voight, Hirschhorn: "PNPLA3 variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease." in: Hepatology (Baltimore, Md.), Vol. 52, Issue 3, pp. 904-12, (2010) (PubMed).
Kamatani, Matsuda, Okada, Kubo, Hosono, Daigo, Nakamura, Kamatani: "Genome-wide association study of hematological and biochemical traits in a Japanese population." in: Nature genetics, Vol. 42, Issue 3, pp. 210-5, (2010) (PubMed).
The enzyme encoded by this gene catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein, and is present in tissues involved in absorption and secretion. This enzyme is a member of the gamma-glutamyltransferase protein family, of which many members have not yet been fully characterized and some of which may represent pseudogenes. This gene is classified as type I gamma-glutamyltransferase. Multiple alternatively spliced variants, encoding the same protein, have been identified.