This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This GTF2IRD2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 467-494 amino acids from the C-terminal region of human GTF2IRD2B.
GTF2IRD2B
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
FITC
Applikationshinweise
WB: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Hinsley, Cunliffe, Tipney, Brass, Tassabehji: "Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome." in: Protein science : a publication of the Protein Society, Vol. 13, Issue 10, pp. 2588-99, (2004) (PubMed).
Tipney, Hinsley, Brass, Metcalfe, Donnai, Tassabehji: "Isolation and characterisation of GTF2IRD2, a novel fusion gene and member of the TFII-I family of transcription factors, deleted in Williams-Beuren syndrome." in: European journal of human genetics : EJHG, Vol. 12, Issue 7, pp. 551-60, (2004) (PubMed).
This gene encodes a glycosylated phosphoprotein with a leucine zipper motif, two helix-loop-helix motifs (I repeats) that are similar to domains found in the TFII-I family of transcription factors, one CHARLIE8 transposable element-like sequence, and a BED zinc finger. This gene lies within a region that is deleted in Williams-Beuren syndrome. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.