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GUCA1C Antikörper (C-Term)

GUCA1C Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB42656 unconjugated
Produktnummer ABIN1881400
  • Target Alle GUCA1C Antikörper anzeigen
    GUCA1C (Guanylate Cyclase Activator 1C (GUCA1C))
    Bindungsspezifität
    • 15
    • 8
    • 3
    • 1
    • 1
    AA 171-199, C-Term
    Reaktivität
    Human
    Wirt
    • 25
    • 2
    Kaninchen
    Klonalität
    • 26
    • 1
    Polyklonal
    Konjugat
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GUCA1C Antikörper ist unkonjugiert
    Applikation
    • 27
    • 13
    • 13
    • 11
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This GUCA1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-199 amino acids from the C-terminal region of human GUCA1C.
    Klon
    RB42656
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product GUCA1C Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Stephen, Palczewski, Sousa: "The crystal structure of GCAP3 suggests molecular mechanism of GCAP-linked cone dystrophies." in: Journal of molecular biology, Vol. 359, Issue 2, pp. 266-75, (2006) (PubMed).

    Imanishi, Li, Sokal, Sowa, Lichtarge, Wensel, Saperstein, Baehr, Palczewski: "Characterization of retinal guanylate cyclase-activating protein 3 (GCAP3) from zebrafish to man." in: The European journal of neuroscience, Vol. 15, Issue 1, pp. 63-78, (2002) (PubMed).

    Haeseleer, Sokal, Li, Pettenati, Rao, Bronson, Wechter, Baehr, Palczewski: "Molecular characterization of a third member of the guanylyl cyclase-activating protein subfamily." in: The Journal of biological chemistry, Vol. 274, Issue 10, pp. 6526-35, (1999) (PubMed).

  • Target
    GUCA1C (Guanylate Cyclase Activator 1C (GUCA1C))
    Andere Bezeichnung
    GUCA1C (GUCA1C Produkte)
    Hintergrund
    GUCA1C stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure.
    Molekulargewicht
    23822
    NCBI Accession
    NP_005450
    UniProt
    O95843
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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