This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This HERC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-77 amino acids from the N-terminal region of human HERC3.
5730409F18Rik antikoerper, AI646603 antikoerper, mKIAA0032 antikoerper, HECT and RLD domain containing E3 ubiquitin protein ligase 3 antikoerper, HECT and RLD domain containing E3 ubiquitin protein ligase 3 L homeolog antikoerper, probable E3 ubiquitin-protein ligase HERC3 antikoerper, hect domain and RLD 3 antikoerper, HERC3 antikoerper, herc3.L antikoerper, herc3 antikoerper, LOC100539754 antikoerper, LOC100563151 antikoerper, Herc3 antikoerper
Hintergrund
HERC3 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).