This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This HSPA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 544-571 amino acids from the C-terminal region of human HSPA6.
HSPA6
Reaktivität: Human
WB
Wirt: Maus
Monoclonal
165f
unconjugated
Applikationshinweise
WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Leung, Hall, Rajendran, Spurr, Lim: "The human heat-shock genes HSPA6 and HSPA7 are both expressed and localize to chromosome 1." in: Genomics, Vol. 12, Issue 1, pp. 74-9, (1992) (PubMed).
Target
HSPA6
(Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6))
HSPA6 antikoerper, HSP70B' antikoerper, heat shock protein family A (Hsp70) member 6 antikoerper, HSPA6 antikoerper
Hintergrund
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.