KISS1R Antikörper (AA 235-263)

Produktnummer ABIN1881480

Produktdetails anti-KISS1R Antikörper

Target: KISS1R (KISS1 Receptor (KISS1R))

Bindungsspezifität: AA 235-263

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KISS1R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This KISS1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-263 amino acids from the Central region of human KISS1R.

Klon: RB40407

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu KISS1R

Target: KISS1R (KISS1 Receptor (KISS1R))

Andere Bezeichnung: KISS1R (KISS1R Produkte)

Synonyme: AXOR12 antikoerper, CPPB1 antikoerper, GPR54 antikoerper, HH8 antikoerper, HOT7T175 antikoerper, KISS-1R antikoerper, Gpr54 antikoerper, KiSS-1 antikoerper, gpr54 antikoerper, gpr54-1 antikoerper, gpr54a antikoerper, kiss1r antikoerper, kiss1rl antikoerper, kissr2 antikoerper, si:dkey-31m5.9 antikoerper, axor12 antikoerper, kissr1a antikoerper, KISS1 receptor antikoerper, KISS1 receptor a antikoerper, KISS1R antikoerper, Kiss1r antikoerper, kiss1ra antikoerper, kiss1r antikoerper

Hintergrund: Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.

Molekulargewicht: 42586

NCBI Accession: NP_115940

UniProt: Q969F8