This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This KRT72 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-342 amino acids from the Central region of human KRT72.
KRT72
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
APC
Applikationshinweise
WB: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Langbein, Rogers, Praetzel, Winter, Schweizer: "K6irs1, K6irs2, K6irs3, and K6irs4 represent the inner-root-sheath-specific type II epithelial keratins of the human hair follicle." in: The Journal of investigative dermatology, Vol. 120, Issue 4, pp. 512-22, (2003) (PubMed).
Porter, Corden, Lunny, Smith, Lane, McLean: "Keratin K6irs is specific to the inner root sheath of hair follicles in mice and humans." in: The British journal of dermatology, Vol. 145, Issue 4, pp. 558-68, (2001) (PubMed).
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. The type II keratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This gene encodes a type II keratin that is specifically expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q12-q13. Multiple transcript variants encoding different isoforms have been found for this gene.