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MAVS Antikörper (N-Term)

MAVS Reaktivität: Maus WB Wirt: Kaninchen Polyclonal RB42373 unconjugated
Produktnummer ABIN1881530
  • Target Alle MAVS Antikörper anzeigen
    MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))
    Bindungsspezifität
    • 15
    • 12
    • 8
    • 8
    • 8
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    Reaktivität
    • 49
    • 37
    • 4
    • 2
    • 1
    Maus
    Wirt
    • 69
    • 7
    Kaninchen
    Klonalität
    • 71
    • 5
    Polyklonal
    Konjugat
    • 34
    • 6
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MAVS Antikörper ist unkonjugiert
    Applikation
    • 68
    • 37
    • 13
    • 13
    • 11
    • 9
    • 9
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Mouse Mavs antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse Mavs.
    Klon
    RB42373
    Isotyp
    Ig Fraction
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  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Ichinohe, Pang, Iwasaki: "Influenza virus activates inflammasomes via its intracellular M2 ion channel." in: Nature immunology, Vol. 11, Issue 5, pp. 404-10, (2010) (PubMed).

  • Target
    MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))
    Andere Bezeichnung
    Mavs (MAVS Produkte)
    Synonyme
    CARDIF antikoerper, IPS-1 antikoerper, IPS1 antikoerper, VISA antikoerper, D430028G21Rik antikoerper, Visa antikoerper, cardif antikoerper, wu:fj20d04 antikoerper, zgc:158392 antikoerper, mitochondrial antiviral signaling protein antikoerper, MAVS antikoerper, Mavs antikoerper, mavs antikoerper
    Hintergrund
    Required for innate immune defense against viruses. Acts downstream of DDX58 and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis (By similarity).
    Molekulargewicht
    53399
    NCBI Accession
    NP_001193314, NP_659137
    UniProt
    Q8VCF0
    Pathways
    Activation of Innate immune Response, Inositol Metabolic Process, Hepatitis C
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