MMP26 Antikörper (AA 96-125)

Produktnummer ABIN1881547

Produktdetails anti-MMP26 Antikörper

Target: MMP26 (Matrix Metallopeptidase 26 (MMP26))

Bindungsspezifität: AA 96-125

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP26 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MMP26 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-125 amino acids from the Central region of human MMP26.

Klon: RB41665

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-MMP26 Antikörper (ABIN1881547)

Liu, Cao, Li, Wu, Wang: "GnRH I and II up-regulate MMP-26 expression through the JNK pathway in human cytotrophoblasts." in: Reproductive biology and endocrinology : RB&E, Vol. 8, pp. 5, (2010) (PubMed).

de Amorim, da Silveira, Queiroz, Galvão, de Souza, de Almeida Freitas: "Matrilysins may not predict the metastatic potential in squamous cell carcinoma of the tongue." in: Acta odontologica Scandinavica, Vol. 68, Issue 4, pp. 228-31, (2010) (PubMed).

Details zu MMP26

Target: MMP26 (Matrix Metallopeptidase 26 (MMP26))

Andere Bezeichnung: MMP26 (MMP26 Produkte)

Synonyme: matrix metallopeptidase 26 antikoerper, MMP26 antikoerper

Hintergrund: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein degrades type IV collagen, fibronectin, fibrinogen, casein, vitronectin, alpha 1-antitrypsin, alpha 2-macroglobulin, and insulin-like growth factor-binding protein 1, and activates MMP9 by cleavage. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain.

Molekulargewicht: 29708

NCBI Accession: NP_068573

UniProt: Q9NRE1