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MTHFR Antikörper (AA 266-292)

MTHFR Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB41196 unconjugated
Produktnummer ABIN1881559
  • Target Alle MTHFR Antikörper anzeigen
    MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))
    Bindungsspezifität
    • 15
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 266-292
    Reaktivität
    • 50
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 45
    • 4
    • 2
    Kaninchen
    Klonalität
    • 49
    • 2
    Polyklonal
    Konjugat
    • 21
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MTHFR Antikörper ist unkonjugiert
    Applikation
    • 38
    • 18
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    B, Pr, M
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This MTHFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-292 amino acids from the Central region of human MTHFR.
    Klon
    RB41196
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product MTHFR Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Singh, Singh, Raman: "MTHFR A1298C polymorphism and idiopathic male infertility." in: Journal of postgraduate medicine, Vol. 56, Issue 4, pp. 267-9, (2010) (PubMed).

    Harisha, Devi, Christopher, Kruthika-Vinod: "Impact of 5,10-methylenetetrahydrofolate reductase gene polymorphism on neural tube defects." in: Journal of neurosurgery. Pediatrics, Vol. 6, Issue 4, pp. 364-7, (2010) (PubMed).

    Wu, Chang, Tsai, Lin, Wang, Tsai, Chen, Yao, Chiu, Bau, Lin: "Significant association of methylenetetrahydrofolate reductase single nucleotide polymorphisms with prostate cancer susceptibility in taiwan." in: Anticancer research, Vol. 30, Issue 9, pp. 3573-7, (2010) (PubMed).

    Magnowski, Seremak-Mrozikiewicz, Nowak-Markwitz, Kurzawińska, Drews, Spaczyński: "[No association between MTHFR 677C>T polymorphism and ovarian cancer risk in BRCA1 mutation carriers in Wielkopolska region]." in: Ginekologia polska, Vol. 81, Issue 7, pp. 506-10, (2010) (PubMed).

    Kristensen, Pedersen, Melsen, Ellehauge, Mejer: "Variants in the dihydropyrimidine dehydrogenase, methylenetetrahydrofolate reductase and thymidylate synthase genes predict early toxicity of 5-fluorouracil in colorectal cancer patients." in: The Journal of international medical research, Vol. 38, Issue 3, pp. 870-83, (2010) (PubMed).

  • Target
    MTHFR (Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))
    Andere Bezeichnung
    MTHFR (MTHFR Produkte)
    Synonyme
    DDBDRAFT_0204686 antikoerper, DDBDRAFT_0230137 antikoerper, DDB_0204686 antikoerper, DDB_0230137 antikoerper, AI323986 antikoerper, methylenetetrahydrofolate reductase (NAD(P)H) L homeolog antikoerper, methylenetetrahydrofolate reductase antikoerper, methylenetetrahydrofolate reductase (NAD(P)H) antikoerper, 5,10-methylenetetrahydrofolate reductase antikoerper, mthfr.L antikoerper, MTHFR antikoerper, mthfr antikoerper, metF antikoerper, DDB_G0279137 antikoerper, Mthfr antikoerper
    Hintergrund
    The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
    Molekulargewicht
    74597
    NCBI Accession
    NP_005948
    UniProt
    P42898
    Pathways
    Methionine Biosynthetic Process
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