NCOA3 Antikörper (N-Term)

Produktnummer ABIN1881566

Produktdetails anti-NCOA3 Antikörper

Target: NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))

Bindungsspezifität: AA 344-372, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCOA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NCOA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-372 amino acids from the N-terminal region of human NCOA3.

Klon: RB41497

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-NCOA3 Antikörper (ABIN1881566)

Cai, Shames, Raso, Xie, Kim, Pollack, Girard, Sullivan, Gao, Peyton, Nanjundan, Byers, Heymach, Mills, Gazdar, Wistuba, Kodadek, Minna: "Steroid receptor coactivator-3 expression in lung cancer and its role in the regulation of cancer cell survival and proliferation." in: Cancer research, Vol. 70, Issue 16, pp. 6477-85, (2010) (PubMed).

Kovanen, Saarikoski, Haukka, Pirkola, Aromaa, Lönnqvist, Partonen: "Circadian clock gene polymorphisms in alcohol use disorders and alcohol consumption." in: Alcohol and alcoholism (Oxford, Oxfordshire), Vol. 45, Issue 4, pp. 303-11, (2010) (PubMed).

Karmakar, Gao, Pace, Oesterreich, Smith: "Cooperative activation of cyclin D1 and progesterone receptor gene expression by the SRC-3 coactivator and SMRT corepressor." in: Molecular endocrinology (Baltimore, Md.), Vol. 24, Issue 6, pp. 1187-202, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Details zu NCOA3

Target: NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))

Andere Bezeichnung: NCOA3 (NCOA3 Produkte)

Synonyme: NCOA3 antikoerper, ACTR antikoerper, AIB-1 antikoerper, AIB1 antikoerper, CAGH16 antikoerper, CTG26 antikoerper, KAT13B antikoerper, RAC3 antikoerper, SRC-3 antikoerper, SRC3 antikoerper, TNRC14 antikoerper, TNRC16 antikoerper, TRAM-1 antikoerper, bHLHe42 antikoerper, pCIP antikoerper, 2010305B15Rik antikoerper, AW321064 antikoerper, Actr antikoerper, Aib1 antikoerper, Rac3 antikoerper, Src3 antikoerper, Tram-1 antikoerper, Tram1 antikoerper, p/Cip antikoerper, pCip antikoerper, actr antikoerper, aib-1 antikoerper, aib1 antikoerper, cagh16 antikoerper, ctg26 antikoerper, kat13b antikoerper, pcip antikoerper, rac3 antikoerper, src-3 antikoerper, src3 antikoerper, tnrc14 antikoerper, tnrc16 antikoerper, tram-1 antikoerper, xSRC-3 antikoerper, nuclear receptor coactivator 3 antikoerper, nuclear receptor coactivator 3 S homeolog antikoerper, NCOA3 antikoerper, Ncoa3 antikoerper, ncoa3.S antikoerper

Hintergrund: The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.

Molekulargewicht: 155293

NCBI Accession: NP_001167559, NP_006525, NP_858045

UniProt: Q9Y6Q9

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha