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POLK Antikörper (AA 531-560)

POLK Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB41936 unconjugated
Produktnummer ABIN1881669
  • Target Alle POLK Antikörper anzeigen
    POLK (Polymerase (DNA Directed) kappa (POLK))
    Bindungsspezifität
    • 15
    • 6
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 531-560
    Reaktivität
    • 54
    • 15
    • 13
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    Human
    Wirt
    • 46
    • 5
    • 3
    Kaninchen
    Klonalität
    • 51
    • 3
    Polyklonal
    Konjugat
    • 25
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser POLK Antikörper ist unkonjugiert
    Applikation
    • 28
    • 20
    • 14
    • 5
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This POLK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-560 amino acids from the Central region of human POLK.
    Klon
    RB41936
    Isotyp
    Ig Fraction
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  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    POLK (Polymerase (DNA Directed) kappa (POLK))
    Andere Bezeichnung
    POLK (POLK Produkte)
    Synonyme
    DINB1 antikoerper, DINP antikoerper, POLQ antikoerper, Dinb1 antikoerper, POLK antikoerper, si:ch211-254o18.3 antikoerper, DNA polymerase kappa antikoerper, polymerase (DNA directed) kappa antikoerper, polymerase (DNA directed), kappa antikoerper, polymerase (DNA directed) kappa L homeolog antikoerper, POLK antikoerper, Polk antikoerper, polk antikoerper, Tb11.01.0080 antikoerper, Tb11.01.0010 antikoerper, Tb11.01.0020 antikoerper, Tb11.01.0030 antikoerper, Tb11.01.0040 antikoerper, Tb11.01.0050 antikoerper, Tb11.12.0001 antikoerper, Tb11.12.0002 antikoerper, Tb11.12.0003 antikoerper, polk.L antikoerper, polk-1 antikoerper
    Hintergrund
    External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass (summary by Lone et al., 2007 [PubMed 17317631]).
    Molekulargewicht
    98809
    NCBI Accession
    NP_057302
    UniProt
    Q9UBT6
    Pathways
    DNA Reparatur
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