This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This POLR2G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-154 amino acids from the C-terminal region of human POLR2G.
POLR2G
Reaktivität: Human
ELISA
Wirt: Maus
Polyclonal
unconjugated
Applikationshinweise
WB: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Cojocaru, Jeronimo, Forget, Bouchard, Bergeron, Côte, Poirier, Greenblatt, Coulombe: "Genomic location of the human RNA polymerase II general machinery: evidence for a role of TFIIF and Rpb7 at both early and late stages of transcription." in: The Biochemical journal, Vol. 409, Issue 1, pp. 139-47, (2007) (PubMed).
Ujvári, Luse: "RNA emerging from the active site of RNA polymerase II interacts with the Rpb7 subunit." in: Nature structural & molecular biology, Vol. 13, Issue 1, pp. 49-54, (2006) (PubMed).
Meka, Werner, Cordell, Onesti, Brick: "Crystal structure and RNA binding of the Rpb4/Rpb7 subunits of human RNA polymerase II." in: Nucleic acids research, Vol. 33, Issue 19, pp. 6435-44, (2005) (PubMed).
Zhou, Deng, Kashanchi, Brady, Shatkin, Kumar: "The Tat/TAR-dependent phosphorylation of RNA polymerase II C-terminal domain stimulates cotranscriptional capping of HIV-1 mRNA." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 22, pp. 12666-71, (2003) (PubMed).
Target
POLR2G
(Polymerase (RNA) II (DNA Directed) Polypeptide G (POLR2G))
RPB19 antikoerper, RPB7 antikoerper, hRPB19 antikoerper, hsRPB7 antikoerper, Rpb7 antikoerper, POLR2G antikoerper, 2410046K11Rik antikoerper, A230108L04Rik antikoerper, C76415 antikoerper, RBP7 antikoerper, Rpo2-7l antikoerper, RNA polymerase II subunit G antikoerper, polymerase (RNA) II (DNA directed) polypeptide G antikoerper, polymerase (RNA) II (DNA directed) polypeptide G L homeolog antikoerper, POLR2G antikoerper, Polr2g antikoerper, polr2g antikoerper, polr2g.L antikoerper
Hintergrund
This gene encodes the seventh largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The protein functions in transcription initiation, and is also thought to help stabilize transcribing polyermase molecules during elongation.