Prolactin Receptor Antikörper (AA 147-179)

Produktnummer ABIN1881684

Produktdetails anti-Prolactin Receptor Antikörper

Target: Prolactin Receptor (PRLR)

Bindungsspezifität: AA 147-179

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Prolactin Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PRLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-179 amino acids from the Central region of human PRLR.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-Prolactin Receptor Antikörper (ABIN1881684)

Kline, Rycyzyn, Clevenger: "Characterization of a novel and functional human prolactin receptor isoform (deltaS1PRLr) containing only one extracellular fibronectin-like domain." in: Molecular endocrinology (Baltimore, Md.), Vol. 16, Issue 10, pp. 2310-22, (2002) (PubMed).

Hu, Meng, Dufau: "Isolation and characterization of two novel forms of the human prolactin receptor generated by alternative splicing of a newly identified exon 11." in: The Journal of biological chemistry, Vol. 276, Issue 44, pp. 41086-94, (2001) (PubMed).

Kline, Roehrs, Clevenger: "Functional characterization of the intermediate isoform of the human prolactin receptor." in: The Journal of biological chemistry, Vol. 274, Issue 50, pp. 35461-8, (2000) (PubMed).

Hu, Zhuang, Meng, Leondires, Dufau: "The human prolactin receptor gene structure and alternative promoter utilization: the generic promoter hPIII and a novel human promoter hP(N)." in: The Journal of clinical endocrinology and metabolism, Vol. 84, Issue 3, pp. 1153-6, (1999) (PubMed).

Boutin, Edery, Shirota, Jolicoeur, Lesueur, Ali, Gould, Djiane, Kelly: "Identification of a cDNA encoding a long form of prolactin receptor in human hepatoma and breast cancer cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 3, Issue 9, pp. 1455-61, (1990) (PubMed).

Details zu Prolactin Receptor

Target: Prolactin Receptor (PRLR)

Andere Bezeichnung: PRLR (PRLR Produkte)

Synonyme: hPRLrI antikoerper, PRL-R antikoerper, prlr antikoerper, PRLRb antikoerper, PRLR antikoerper, tprlr antikoerper, DKFZp469D061 antikoerper, RATPRLR antikoerper, AI987712 antikoerper, Pr-1 antikoerper, Pr-3 antikoerper, Prlr-rs1 antikoerper, wu:fj65c07 antikoerper, prolactin receptor antikoerper, prolactin receptor L homeolog antikoerper, prolactin receptor S homeolog antikoerper, prolactin receptor a antikoerper, PRLR antikoerper, prlr.L antikoerper, prlr.S antikoerper, PR antikoerper, prlr antikoerper, Prlr antikoerper, prlra antikoerper

Hintergrund: This is a receptor for the anterior pituitary hormone prolactin (PRL). Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.

Molekulargewicht: 69506

NCBI Accession: NP_000940, NP_001191243, NP_001191244, NP_001191245, NP_001191246, NP_001191247

UniProt: P16471

Pathways: JAK-STAT Signalweg, Response to Growth Hormone Stimulus