This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This PRPS1L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-106 amino acids from the N-terminal region of human PRPS1L1.
PRPS1L1
Reaktivität: Human
WB, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 555
Applikationshinweise
WB: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Venter, Adams, Myers, Li, Mural, Sutton, Smith, Yandell, Evans, Holt, Gocayne, Amanatides, Ballew, Huson, Wortman, Zhang, Kodira, Zheng, Chen, Skupski, Subramanian, Thomas, Zhang, Gabor Miklos et al.: "The sequence of the human genome. ..." in: Science (New York, N.Y.), Vol. 291, Issue 5507, pp. 1304-51, (2001) (PubMed).
Taira, Iizasa, Shimada, Kudoh, Shimizu, Tatibana: "A human testis-specific mRNA for phosphoribosylpyrophosphate synthetase that initiates from a non-AUG codon." in: The Journal of biological chemistry, Vol. 265, Issue 27, pp. 16491-7, (1990) (PubMed).
This intronless gene is specifically expressed in the testis, and encodes a protein that is highly homologous to the two subunits of phosphoribosylpyrophosphate synthetase encoded by human X-linked genes, PRPS1 and PRPS2. These enzymes convert pyrimidine, purine or pyridine bases to the corresponding ribonucleoside monophosphates. In vitro transcription/translation and site-directed mutagenesis studies indicate that translation of this mRNA initiates exclusively at a non-AUG (ACG) codon. [provided by RefSeq].