PRRX2 Antikörper (C-Term)

Produktnummer ABIN1881691

Produktdetails anti-PRRX2 Antikörper

Target: PRRX2 (Paired Related Homeobox 2 (PRRX2))

Bindungsspezifität: AA 223-250, C-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRRX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PRRX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-250 amino acids from the C-terminal region of human PRRX2.

Klon: RB37428

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-PRRX2 Antikörper (ABIN1881691)

Gervais, Mauvieux, Perrusson, Hélias, Struski, Leymarie, Lioure, Lessard: "A new translocation t(9;11)(q34;p15) fuses NUP98 to a novel homeobox partner gene, PRRX2, in a therapy-related acute myeloid leukemia." in: Leukemia, Vol. 19, Issue 1, pp. 145-8, (2004) (PubMed).

Details zu PRRX2

Target: PRRX2 (Paired Related Homeobox 2 (PRRX2))

Andere Bezeichnung: PRRX2 (PRRX2 Produkte)

Synonyme: Prx2 antikoerper, PRRX2 antikoerper, PMX2 antikoerper, PRX2 antikoerper, S8 antikoerper, (S8) antikoerper, PRX-2 antikoerper, paired related homeobox 2 antikoerper, Prrx2 antikoerper, PRRX2 antikoerper

Hintergrund: The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation.

Molekulargewicht: 27079

NCBI Accession: NP_057391

UniProt: Q99811