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PSMD12 Antikörper (AA 276-304)
PSMD12
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
RB42427
unconjugated
Produktnummer ABIN1881697
Produktdetails anti-PSMD12 Antikörper
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Target
Alle PSMD12 Antikörper anzeigen
PSMD12
(Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))
Bindungsspezifität
Alle Epitope für PSMD12 Antikörper
AA 276-304
Reaktivität
Alle Reaktivitäten für PSMD12 Antikörper
Human
Wirt
Alle Wirte für PSMD12 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für PSMD12 Antikörper
Polyklonal
Konjugat
Alle Konjugate für PSMD12 Antikörper
Dieser PSMD12 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für PSMD12 Antikörper
Western Blotting (WB)
Homologie
B
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This PSMD12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276-304 amino acids from the Central region of human PSMD12.
Klon
RB42427
Isotyp
Ig Fraction
Top Product
Discover our top product PSMD12 Primärantikörper
Alternativen
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anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12) (N-Term) antibody
PSMD12
Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Hund, Schwein, Affe, Hamster
WB
Wirt: Kaninchen
Polyclonal
unconjugated
anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12) (Middle Region) antibody
PSMD12
Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Hund, Zebrafisch (Danio rerio), Kaninchen
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
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Applikationshinweise
WB: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Referenzen für anti-PSMD12 Antikörper (ABIN1881697)
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Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al. : "Large-scale mapping of human protein-protein interactions by mass spectrometry. ... " in: Molecular systems biology , Vol. 3 , pp. 89 , (2007 ) (PubMed ).
Gandhi, Zhong, Mathivanan, Karthick, Chandrika, Mohan, Sharma, Pinkert, Nagaraju, Periaswamy, Mishra, Nandakumar, Shen, Deshpande, Nayak, Sarker, Boeke, Parmigiani, Schultz, Bader, Pandey : "Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets. " in: Nature genetics , Vol. 38 , Issue 3 , pp. 285-93 , (2006 ) (PubMed ).
Listovsky, Oren, Yudkovsky, Mahbubani, Weiss, Lebendiker, Brandeis : "Mammalian Cdh1/Fzr mediates its own degradation. " in: The EMBO journal , Vol. 23 , Issue 7 , pp. 1619-26 , (2004 ) (PubMed ).
Bouwmeester, Bauch, Ruffner, Angrand, Bergamini, Croughton, Cruciat, Eberhard, Gagneur, Ghidelli, Hopf, Huhse, Mangano, Michon, Schirle, Schlegl, Schwab, Stein, Bauer, Casari, Drewes, Gavin, Jackson et al. : "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. ... " in: Nature cell biology , Vol. 6 , Issue 2 , pp. 97-105 , (2004 ) (PubMed ).
Details zu PSMD12
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Target
PSMD12
(Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))
Andere Bezeichnung
PSMD12 (PSMD12 Produkte )
Synonyme
wu:fb38a06 antikoerper, wu:fc34f08 antikoerper, wu:fc49f02 antikoerper, PSMD12 antikoerper, rpn5 antikoerper, Rpn5 antikoerper, p55 antikoerper, 1500002F15Rik antikoerper, AI480719 antikoerper, P55 antikoerper, proteasome 26S subunit, non-ATPase 12 antikoerper, proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 antikoerper, psmd12 antikoerper, PSMD12 antikoerper, Psmd12 antikoerper
Hintergrund
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3.
Molekulargewicht
52904
NCBI Accession
NP_002807 , NP_777360
UniProt
O00232
Pathways
Mitotic G1-G1/S Phases , DNA Replication , Synthesis of DNA , Ubiquitin Proteasome Pathway
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