PTRH2 Antikörper (N-Term)

Produktnummer ABIN1881706

Produktdetails anti-PTRH2 Antikörper

Target: PTRH2 (Peptidyl-tRNA Hydrolase 2 (PTRH2))

Bindungsspezifität: AA 26-55, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTRH2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PTRH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human PTRH2.

Klon: RB42733

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-PTRH2 Antikörper (ABIN1881706)

Fan, Jiang, Suo, Liu, Xu, Ji, Zhang, Yang: "Down-regulation of the apoptosis-inducing factor or Bcl-2 inhibitor of transcription by RNA interference can alleviate TAp63gamma-induced apoptosis in esophageal squamous carcinoma EC9706 cells." in: International journal of oncology, Vol. 35, Issue 2, pp. 359-67, (2009) (PubMed).

Biliran, Jan, Chen, Pasquale, Ruoslahti: "Protein kinase D is a positive regulator of Bit1 apoptotic function." in: The Journal of biological chemistry, Vol. 283, Issue 42, pp. 28029-37, (2008) (PubMed).

Bouchentouf, Benabdallah, Rousseau, Schwartz, Tremblay: "Induction of Anoikis following myoblast transplantation into SCID mouse muscles requires the Bit1 and FADD pathways." in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, Vol. 7, Issue 6, pp. 1491-505, (2007) (PubMed).

De Pereda, Waas, Jan, Ruoslahti, Schimmel, Pascual: "Crystal structure of a human peptidyl-tRNA hydrolase reveals a new fold and suggests basis for a bifunctional activity." in: The Journal of biological chemistry, Vol. 279, Issue 9, pp. 8111-5, (2004) (PubMed).

Details zu PTRH2

Target: PTRH2 (Peptidyl-tRNA Hydrolase 2 (PTRH2))

Andere Bezeichnung: PTRH2 (PTRH2 Produkte)

Synonyme: BIT1 antikoerper, PTH2 antikoerper, A230072I16Rik antikoerper, Bit1 antikoerper, CGI-147 antikoerper, wu:fj09f02 antikoerper, zgc:109954 antikoerper, RGD1306819 antikoerper, peptidyl-tRNA hydrolase 2 antikoerper, ptrh2 antikoerper, CC1G_10259 antikoerper, ANI_1_1036184 antikoerper, AOR_1_2082154 antikoerper, PTRH2 antikoerper, Ptrh2 antikoerper

Hintergrund: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis (By similarity). Promotes caspase-independent apoptosis by regulating the function of two transcriptional regulators, AES and TLE1.

Molekulargewicht: 19194

NCBI Accession: NP_057161

UniProt: Q9Y3E5