CASK Antikörper (AA 589-616)

Produktnummer ABIN1881710

Produktdetails anti-CASK Antikörper

Target: CASK (Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK))

Bindungsspezifität: AA 589-616

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CASK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: H, M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Rat Cask antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 589-616 amino acids from the Central region of rat Cask.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-CASK Antikörper (ABIN1881710)

Tabuchi, Biederer, Butz, Sudhof: "CASK participates in alternative tripartite complexes in which Mint 1 competes for binding with caskin 1, a novel CASK-binding protein." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 22, Issue 11, pp. 4264-73, (2002) (PubMed).

Chetkovich, Bunn, Kuo, Kawasaki, Kohwi, Bredt: "Postsynaptic targeting of alternative postsynaptic density-95 isoforms by distinct mechanisms." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 22, Issue 15, pp. 6415-25, (2002) (PubMed).

Hsueh, Wang, Yang, Sheng: "Nuclear translocation and transcription regulation by the membrane-associated guanylate kinase CASK/LIN-2." in: Nature, Vol. 404, Issue 6775, pp. 298-302, (2000) (PubMed).

Butz, Okamoto, Südhof: "A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain." in: Cell, Vol. 94, Issue 6, pp. 773-82, (1998) (PubMed).

Hata, Butz, Südhof: "CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 16, Issue 8, pp. 2488-94, (1996) (PubMed).

Details zu CASK

Target: CASK (Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK))

Andere Bezeichnung: Cask (CASK Produkte)

Synonyme: CAKI antikoerper, CAMGUK antikoerper, CG13412 antikoerper, CG13413 antikoerper, CG6703 antikoerper, CMG antikoerper, CMG/CASK antikoerper, Caki antikoerper, CamGUK antikoerper, CamguK antikoerper, Camguk antikoerper, Cask antikoerper, Cmg antikoerper, DLin-2 antikoerper, Dmel\\CG6703 antikoerper, RE09582p antikoerper, caki antikoerper, camguk antikoerper, cmg antikoerper, dCASK antikoerper, wu:fb70g06 antikoerper, CAGH39 antikoerper, FGS4 antikoerper, LIN2 antikoerper, MICPCH antikoerper, MRXSNA antikoerper, TNRC8 antikoerper, DXPri1 antikoerper, DXRib1 antikoerper, LIN-2 antikoerper, Pals3 antikoerper, mLin-2 antikoerper, CG6703 gene product from transcript CG6703-RF antikoerper, Peripheral plasma membrane protein CASK antikoerper, CAMK/CASK protein kinase antikoerper, peripheral plasma membrane protein CASK antikoerper, calcium/calmodulin-dependent serine protein kinase b antikoerper, calcium/calmodulin-dependent serine protein kinase a antikoerper, calcium/calmodulin dependent serine protein kinase antikoerper, calcium/calmodulin-dependent serine protein kinase (MAGUK family) antikoerper, calcium/calmodulin-dependent serine protein kinase (MAGUK family) S homeolog antikoerper, CASK antikoerper, Bm1_33725 antikoerper, LOAG_17286 antikoerper, Tsp_03763 antikoerper, caskb antikoerper, caska antikoerper, Cask antikoerper, cask.S antikoerper

Hintergrund: Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TRB1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins, and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1.

Molekulargewicht: 103259

NCBI Accession: NP_071520

UniProt: Q62915

Pathways: Synaptic Vesicle Exocytosis