Retinoic Acid Early Transcript 1E (RAET1E) (AA 150-179) Antikörper

Produktnummer ABIN1881724

Produktdetails

Target: Retinoic Acid Early Transcript 1E (RAET1E)

Bindungsspezifität: AA 150-179

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RAET1E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-179 amino acids from the Central region of human RAET1E.

Klon: RB40835

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Antigendetails

Target: Retinoic Acid Early Transcript 1E (RAET1E)

Andere Bezeichnung: RAET1E (RAET1E Produkte)

Synonyme: LETAL antikoerper, N2DL-4 antikoerper, NKG2DL4 antikoerper, RAET1E2 antikoerper, RL-4 antikoerper, ULBP4 antikoerper, bA350J20.7 antikoerper, retinoic acid early transcript 1E antikoerper, RAET1E antikoerper, Raet1e antikoerper

Hintergrund: Members of the RAET1 family, such as RAET1E, are major histocompatibility complex (MHC) class I-related genes located within a 180-kb cluster on chromosome 6q24.2-q25.3. RAET1 proteins contain MHC class I-like alpha-1 and alpha-2 domains. RAET1E and RAET1G (MIM 609244) differ from the other RAET1 proteins (e.g., RAET1I, or ULBP1, MIM 605697) in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. RAET1E is a ligand for NKG2D (KLRK1, MIM 611817), which is expressed on the surface of several types of immune cells and is involved in innate and adaptive immune responses (summary by Radosavljevic et al. (2002) [PubMed 11827464] and Cao et al. (2007) [PubMed 17470428]).

Molekulargewicht: 30122

NCBI Accession: NP_001230254, NP_001230256, NP_001230257, NP_631904

UniProt: Q8TD07