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RGS13 Antikörper (AA 61-90)

RGS13 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB40445 unconjugated
Produktnummer ABIN1881748
  • Target Alle RGS13 Antikörper anzeigen
    RGS13 (Regulator of G-Protein Signaling 13 (RGS13))
    Bindungsspezifität
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 61-90
    Reaktivität
    • 25
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Human
    Wirt
    • 20
    • 4
    • 1
    Kaninchen
    Klonalität
    • 22
    • 3
    Polyklonal
    Konjugat
    • 20
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RGS13 Antikörper ist unkonjugiert
    Applikation
    • 22
    • 13
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This RGS13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-90 amino acids from the Central region of human RGS13.
    Klon
    RB40445
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product RGS13 Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Wang, Lippman, Lee, Yang, Khuri, Kim, Lin, Chang, Lotan, Hong, Wu: "Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma." in: Carcinogenesis, Vol. 31, Issue 10, pp. 1755-61, (2010) (PubMed).

    Bansal, DiVietro, Kuehn, Rao, Nocka, Gilfillan, Druey: "RGS13 controls g protein-coupled receptor-evoked responses of human mast cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 11, pp. 7882-90, (2008) (PubMed).

    Han, Huang, Kim, Kehrl: "RGS1 and RGS13 mRNA silencing in a human B lymphoma line enhances responsiveness to chemoattractants and impairs desensitization." in: Journal of leukocyte biology, Vol. 79, Issue 6, pp. 1357-68, (2006) (PubMed).

    Islam, Asplund, Lindvall, Nygren, Liden, Kimby, Christensson, Smith, Sander: "High level of cannabinoid receptor 1, absence of regulator of G protein signalling 13 and differential expression of Cyclin D1 in mantle cell lymphoma." in: Leukemia, Vol. 17, Issue 9, pp. 1880-90, (2003) (PubMed).

  • Target
    RGS13 (Regulator of G-Protein Signaling 13 (RGS13))
    Andere Bezeichnung
    RGS13 (RGS13 Produkte)
    Synonyme
    RGD1562103 antikoerper, regulator of G protein signaling 13 antikoerper, regulator of G-protein signaling 13 antikoerper, RGS13 antikoerper, Rgs13 antikoerper
    Hintergrund
    The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist.
    Molekulargewicht
    19135
    NCBI Accession
    NP_002918, NP_658912
    UniProt
    O14921
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling
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