RRM1 Antikörper (N-Term)
(2 Referenzen)-
- Target Alle RRM1 Antikörper anzeigen
- RRM1 (Ribonucleotide Reductase M1 (RRM1))
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Bindungsspezifität
- AA 71-100, N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RRM1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Homologie
- M
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This RRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-100 amino acids from the N-terminal region of human RRM1.
- Klon
- RB42407
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product RRM1 Primärantikörper
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anti-Ribonucleotide Reductase M1 (RRM1) (AA 541-792) antibody
RRM1 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Maus Monoclonal 2D6D8 unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (AA 593-792) antibodyRRM1 Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (AA 1-213) antibodyRRM1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (Center) antibodyRRM1 Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (AA 593-792) antibodyRRM1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1D6 unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (AA 541-792) antibodyRRM1 Reaktivität: Human WB, IHC, IHC (p) Wirt: Maus Monoclonal 5G5 unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (AA 733-778) antibodyRRM1 Reaktivität: Human ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) antibodyRRM1 Reaktivität: Human, Maus WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) (Internal Region) antibodyRRM1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Ribonucleotide Reductase M1 (RRM1) antibodyRRM1 Reaktivität: Human ELISA, IHC Wirt: Maus Monoclonal 3D6H5 unconjugated
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- Applikationshinweise
- WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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: "Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection." in: Molecular human reproduction, Vol. 16, Issue 10, pp. 770-7, (2010) (PubMed).
: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).
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: "Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection." in: Molecular human reproduction, Vol. 16, Issue 10, pp. 770-7, (2010) (PubMed).
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- Target
- RRM1 (Ribonucleotide Reductase M1 (RRM1))
- Andere Bezeichnung
- RRM1 (RRM1 Produkte)
- Hintergrund
- This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.
- Molekulargewicht
- 90070
- NCBI Accession
- NP_001024
- UniProt
- P23921
- Pathways
- Positive Regulation of Endopeptidase Activity
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