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SIKE1 Antikörper (N-Term)

SIKE1 Reaktivität: Maus WB Wirt: Kaninchen Polyclonal RB42417 unconjugated
Produktnummer ABIN1881808
  • Target Alle SIKE1 Antikörper anzeigen
    SIKE1 (Suppressor of IKBKE 1 (SIKE1))
    Bindungsspezifität
    • 13
    • 9
    • 8
    • 7
    • 6
    AA 36-63, N-Term
    Reaktivität
    • 19
    • 17
    • 2
    Maus
    Wirt
    • 32
    Kaninchen
    Klonalität
    • 32
    Polyklonal
    Konjugat
    • 12
    • 4
    • 4
    • 4
    • 4
    • 4
    Dieser SIKE1 Antikörper ist unkonjugiert
    Applikation
    • 32
    • 26
    • 14
    • 2
    Western Blotting (WB)
    Homologie
    Rat
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Mouse Sike1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-63 amino acids from the N-terminal region of mouse Sike1.
    Klon
    RB42417
    Isotyp
    Ig Fraction
    Top Product
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  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Katayama, Tomaru, Kasukawa, Waki, Nakanishi, Nakamura, Nishida, Yap, Suzuki, Kawai, Suzuki, Carninci, Hayashizaki, Wells, Frith, Ravasi, Pang, Hallinan, Mattick, Hume, Lipovich, Batalov et al.: "Antisense transcription in the mammalian transcriptome...." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1564-6, (2005) (PubMed).

  • Target
    SIKE1 (Suppressor of IKBKE 1 (SIKE1))
    Andere Bezeichnung
    Sike1 (SIKE1 Produkte)
    Synonyme
    SIKE antikoerper, 2810005O12Rik antikoerper, 5730470L24Rik antikoerper, AI450236 antikoerper, AI839862 antikoerper, Sike antikoerper, Sikeb antikoerper, RGD1311316 antikoerper, suppressor of IKBKE 1 antikoerper, SIKE1 antikoerper, Sike1 antikoerper
    Hintergrund
    Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus-and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity).
    Molekulargewicht
    23522
    NCBI Accession
    NP_079955
    UniProt
    Q9CPR7
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