SMAD6 Antikörper (C-Term)
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- Target Alle SMAD6 Antikörper anzeigen
- SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
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Bindungsspezifität
- AA 357-386, C-Term
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SMAD6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This SMAD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 357-386 amino acids from the C-terminal region of human SMAD6.
- Klon
- RB41931
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product SMAD6 Primärantikörper
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- Applikationshinweise
- WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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Defective bone morphogenic protein signaling underlies hepcidin deficiency in HFE hereditary hemochromatosis." in: Hepatology (Baltimore, Md.), Vol. 52, Issue 4, pp. 1266-73, (2010) (PubMed).
: "Downregulation of SMAD2, 4 and 6 mRNA and TGFbeta receptor I mRNA in lesional and non-lesional psoriatic skin." in: Acta dermato-venereologica, Vol. 89, Issue 4, pp. 351-6, (2009) (PubMed).
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Defective bone morphogenic protein signaling underlies hepcidin deficiency in HFE hereditary hemochromatosis." in: Hepatology (Baltimore, Md.), Vol. 52, Issue 4, pp. 1266-73, (2010) (PubMed).
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- Target
- SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
- Andere Bezeichnung
- SMAD6 (SMAD6 Produkte)
- Synonyme
- madh6 antikoerper, madh7 antikoerper, Xsmad6 antikoerper, hst17432 antikoerper, AOVD2 antikoerper, HsT17432 antikoerper, MADH6 antikoerper, MADH7 antikoerper, Madh6 antikoerper, b2b390Clo antikoerper, Smad6-like antikoerper, smad6 antikoerper, wu:fb22g05 antikoerper, SMAD family member 6 antikoerper, SMAD family member 6a antikoerper, smad6 antikoerper, SMAD6 antikoerper, Smad6 antikoerper, smad6a antikoerper
- Hintergrund
- The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants encoding different isoforms have been found for this gene.
- Molekulargewicht
- 53497
- NCBI Accession
- NP_001136333, NP_005576
- UniProt
- O43541
- Pathways
- Chromatin Binding
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