Syntaxin 11 Antikörper (N-Term)

Produktnummer ABIN1881853

Produktdetails anti-Syntaxin 11 Antikörper

Target: Syntaxin 11 (STX11)

Bindungsspezifität: AA 29-56, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Syntaxin 11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This STX11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-56 amino acids from the N-terminal region of human STX11.

Klon: RB40556

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-Syntaxin 11 Antikörper (ABIN1881853)

Marsh, Satake, Biroschak, Jacobs, Johnson, Jordan, Bleesing, Filipovich, Zhang: "STX11 mutations and clinical phenotypes of familial hemophagocytic lymphohistiocytosis in North America." in: Pediatric blood & cancer, Vol. 55, Issue 1, pp. 134-40, (2010) (PubMed).

zur Stadt, Rohr, Seifert, Koch, Grieve, Pagel, Strauss, Kasper, Nürnberg, Becker, Maul-Pavicic, Beutel, Janka, Griffiths, Ehl, Hennies: "Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11." in: American journal of human genetics, Vol. 85, Issue 4, pp. 482-92, (2009) (PubMed).

Marcelin, Diatloff-Zito, Nicole, Robert: "Developmental methylation program and concerted expression of Stx11 in mouse tissues." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 20, Issue 3, pp. 131-9, (2009) (PubMed).

Details zu Syntaxin 11

Target: Syntaxin 11 (STX11)

Andere Bezeichnung: STX11 (STX11 Produkte)

Synonyme: MGC79075 antikoerper, MGC89708 antikoerper, FHL4 antikoerper, HLH4 antikoerper, HPLH4 antikoerper, 5830405C08Rik antikoerper, syntaxin 11 antikoerper, syntaxin 11 S homeolog antikoerper, STX11 antikoerper, stx11.S antikoerper, stx11 antikoerper, Stx11 antikoerper

Hintergrund: This gene encodes a member of the syntaxin family. Syntaxins have been implicated in the targeting and fusion of intracellular transport vesicles. This family member may regulate protein transport among late endosomes and the trans-Golgi network. Mutations in this gene have been associated with familial hemophagocytic lymphohistiocytosis.

Molekulargewicht: 33196

NCBI Accession: NP_003755

UniProt: O75558