This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This Mouse Tbkbp1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 470-497 amino acids from the C-terminal region of mouse Tbkbp1.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Ryzhakov, Randow: "SINTBAD, a novel component of innate antiviral immunity, shares a TBK1-binding domain with NAP1 and TANK." in: The EMBO journal, Vol. 26, Issue 13, pp. 3180-90, (2007) (PubMed).
Zambrowicz, Abuin, Ramirez-Solis, Richter, Piggott, BeltrandelRio, Buxton, Edwards, Finch, Friddle, Gupta, Hansen, Hu, Huang, Jaing, Key, Kipp, Kohlhauff, Ma, Markesich, Payne, Potter, Qian, Shaw et al.: "Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 24, pp. 14109-14, (2003) (PubMed).
Adapter protein which constitutively binds TBK1 and IKBKE and may play a role in antiviral innate immunity. Essential for the efficient induction of IRF-dependent transcription following infection with Sendai virus.